Eve Harper lives in an apocalyptic future, eighty years from now, where humans are all but wiped out by a man-made virus. Humans that remain, live in walled-off cities called strongholds that protect them from the mutated creatures and dangers of the wasteland outside the walls. Eve is a courier-for-hire, who travels from stronghold to stronghold getting paid to carry goods across the wasteland, along with her mechanical sidekick, ARTIE. When Eve and her brother were kids, their parents were killed in a raid on their commune by a local tribe. Ever since then, Eve only worries about two things: herself and her brother. Everything else is just a job to her.